WebJun 14, 2024 · According to the cholesterol treatment trialists’ (CTT) analysis LDL-C lowering by more than 40% should have yielded a dramatic reduction of cardiovascular events in this high-risk patient population. WebMar 9, 2011 · In the human population, there exist low absorbers and high synthesisers and, inversely, this could explain a variable and complementary efficiency of drugs, which inhibit absorption or synthesis. However, it is not possible to predict these effects on the basal levels of plasma PS or cholesterol precursors (lathosterol).
Prognostic significance of serum cholesterol, lathosterol, and ... - Pub…
WebLathosterol is a natural product found in Smilax perfoliata, Nothoscordum montevidense, and other organisms with data available. 5alpha-cholest-7-en-3beta-ol is a cholestanoid … WebNov 1, 1989 · A high serum level of cholesterol precursor lathosterol, a high lathosterol/ sitosterol ratio and sterol balance data suggest that cholesterol synthesis may be slightly higher in the apo E 3 3 than E 4 3 group. The findings indicate that the genetically determined apo E polymorphism contributes to cholesterol absorption efficiency in FH ... pleco graded reader
1.6: Sterols and Sterol Induced Phases - Physics LibreTexts
WebOct 14, 2024 · Single nucleotide polymorphisms (SNPs) have been associated with cholesterol metabolism and may partly explain large inter-individual variability in intestinal cholesterol absorption and endogenous cholesterol synthesis rates. This cross-sectional study therefore examined whether SNPs in genes encoding for proteins involved in … WebJan 24, 2011 · Low lathosterol, sitosterol, and cholesterol predicted mortality additively and independently of each other. When all three sterols were high (> median) or low, the age- and gender-adjusted survival was 9.9 and 5.6 years (P < 0.001). Conclusion. Lower synthesis and absorption of cholesterol, and low serum cholesterol level are associated with ... WebAug 20, 2013 · Especially those with the highest lathosterol but the lowest campesterol levels at baseline had significantly less LDL-C reduction than those with the same baseline lathosterol levels but the... prince of wales norwich