Cthrc1 cancer
WebFeb 15, 2024 · In CRC, the deletion of SMAD4 in cancer cells resulted in a decrease in S100A8+ monocytes in the tumor microenvironment . Furthermore, the release of Collagen Triple Helix Repeat Containing 1 (CTHRC1) by CRC cells induced M2 polarization of TAMs through TGFβ signaling and further promoted hepatic metastasis in mouse models … WebOct 6, 2024 · In the current study, we comprehensively analyzed CTHRC1 in distinct human cancer subtypes for the first time and find more closely CTHRC1-associated cancer …
Cthrc1 cancer
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WebMar 1, 2024 · Collagen triple helix repeat containing 1 (CTHRC1) protein is known to be involved in tissue remodeling processes and closely associated with carcinogenesis and … WebMar 21, 2024 · CTHRC1 (Collagen Triple Helix Repeat Containing 1) is a Protein Coding gene. Diseases associated with CTHRC1 include Barrett Esophagus and Adenocarcinoma . Among its related pathways are Wnt …
WebJ Cancer 2016; 7(15):2213-2220. doi:10.7150/jca.16539 This issue Cite. Review. Multidimensional Roles of Collagen Triple Helix Repeat Containing 1 (CTHRC1) in Malignant Cancers . Neng Jiang 1*, … WebMar 1, 2024 · Collagen triple helix repeat containing 1 (CTHRC1) is a glycosylated protein secreted during tissue repair, which reduces collagen matrix deposition and …
WebCTHRC1. PROTEIN SUMMARY SECTION OVERVIEW RNA DATA ANTIBODY DATA. CTHRC1 INFORMATION. Proteini. Full gene name according to HGNC. Collagen triple helix repeat containing 1. Gene namei. Official gene symbol, which is typically a short form of the gene name, according to HGNC. CTHRC1. WebCTHRC1 has a role in pancreatic cancer progression and metastasis by regulating migration and adhesion activities of cancer cells. PMID: 23222813; Data indicate that the upregulated expression of collagen triple helix repeat containing 1 (CTHRC1) in gastric carcinogenesis contributes to tumor cell invasion and metastasis.
WebNov 14, 2024 · Although recent researches have reported that CTHRC1 upregulation in breast cancer promoting cell proliferation, invasion and migration could be through activating GSK-3β/β-catenin signaling, Citation 41 the exact mechanisms of CTHRC1 involvement in breast cancer remains unclear. Therefore, high expression of CTHRC1 …
WebJul 19, 2024 · Collagen triple helix repeat containing-1 (CTHRC1), highly expressed in multiple human solid tumors, has been identified as a tumor associated protein. However, its specific role and mechanism with immune infiltrates in gastric cancer are still unclear. In this study, we systematically explored and validated the expression and prognostic value of … how is lyme disease diagWebCollagen triple helix repeat containing-1 (CTHRC1) has been identified as cancer-related protein. CTHRC1 expresses mainly in adventitial fibroblasts and neointimal smooth muscle cells of balloon ... how is lyme disease treatedWebCollagen triple helix repeat containing 1 (CTHRC1) is a secreted glycoprotein that decreases the deposition of collagen matrix and accelerates tumor metastasis. However, the relationship between CTHRC1 and the outcomes of head and neck squamous cell carcinoma (HNSCC) and tumor‑infiltrating lymphocytes remains unclear. In the present … how is lymphedema diagnosed and confirmedWebMar 30, 2012 · The gene, collagen triple helix repeat containing 1 (CTHRC1), has been reported to increase in several kinds of human solid cancers and is associated with tumor invasion and metastasis.To date, the expression and function of CTHRC1 in gastric cancer (GC) have not been reported. how is lymph different than plasmaWebOct 22, 2024 · The association of CTHRC1 with tumor progression is demonstrated in various human cancers, including hepatocellular carcinoma, gastric cancer, pancreatic cancer, GIST and colorectal cancer (1-3).In a meta-analysis done by Wang et al., the results revealed correlation of CTHRC1 expression with TNM stage in gastric cancer, … how is lymphatic filariasis spreadWebJun 20, 2024 · This study aimed to investigate the prognostic value of CTHRC1, and further explore its association with immune infiltration in breast cancer. Methods: CTHRC1 … how is lymphedema gradedWebMar 1, 2024 · Collagen triple helix repeat containing 1 (CTHRC1) is a glycosylated protein secreted during tissue repair, which reduces collagen matrix deposition and promotes cell migration. ... Studies have shown that CTHRC1 promotes colorectal cancer metastasis by inducing the Wnt/PCP signal transduction (Yang et al., 2015). In … how is lymph different from plasma